What TV doesn't, print can't; we deliver.
What TV doesn't, print can't; we deliver.
The World Retinoblastoma Week, observed from May 14th to 20th this year, aims to raise awareness about retinoblastoma, the most common type of cancer found in children. It is a life-threatening disease that originates in the retina, the crucial lining at the back of the eye. While primarily affecting newborns to five-year-olds, studies show that 40% of cases involve mutations in the RB gene.
In a conversation with The New Indian, Dr. Rima Dada, Professor In-charge of the Media Cell and Laboratory for Molecular Reproduction and Genetics at the Department of Anatomy, explains that retinoblastoma is a genetic disease with both heritable and non heritable forms. Through targeted exome sequencing, their research revealed mutations in various oncogenes and tumor suppressor genes, shedding light on the complexity of the condition beyond the RB gene.
Dr. Dada emphasizes the role of unhealthy lifestyle factors that contribute to the disease. Smoking, alcohol consumption, excessive cell phone use, psychological stress, anxiety, depression, exposure to insecticides, pesticides, and repeated infections generate oxidative stress, leading to DNA damage.
The delay in marriage and childbirth has also been linked to increased risk. Dr. Dada explains, “When the age of marriage and having a child is delayed, and the parents are older, the risk of retinoblastoma in the last-born child increases. The poor quality of DNA in the father, resulting from an unhealthy lifestyle, such as smoking, alcohol consumption, and severe psychological stress, causes DNA damage that can be passed on to the fetus, leading to cancers and neurodevelopmental disorders.”
Dr. Dada underscores the significance of yoga, stating that regular practice can reduce oxidative stress within a month, while DNA damage improvement becomes significant after six months of daily practice for at least half an hour.
Retinoblastoma remains a largely misunderstood condition, with approximately one child in every 8,000 being affected worldwide. India is among the top three countries reporting nearly half of the total cases. Early detection plays a crucial role in successful treatment and complete recovery. Increased awareness is crucial to saving young lives from this devastating disease.
